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Complement-mediated cytotoxic effects on pancreatic islets with sera from diabetic patients

H G Rittenhouse, D L Oxender, S Pek

    Diabetes
    |April 1, 1980
    PubMed
    Summary

    Serum from some juvenile-onset diabetes patients shows a complement-dependent cytotoxic effect on pancreatic islets. This suggests a potential autoimmune role in juvenile-onset diabetes pathogenesis.

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