Disorders of phagocyte chemotaxis

Related Experiment Video

Updated: May 1, 2026

Quantifying Human Monocyte Chemotaxis In Vitro and Murine Lymphocyte Trafficking In Vivo
08:38

Quantifying Human Monocyte Chemotaxis In Vitro and Murine Lymphocyte Trafficking In Vivo

Published on: October 30, 2017

6.9K

J I Gallin, D G Wright, H L Malech

    Annals of Internal Medicine
    |April 1, 1980
    PubMed

    More Related Videos

    Time-lapse Imaging of Mouse Macrophage Chemotaxis09:33

    Time-lapse Imaging of Mouse Macrophage Chemotaxis

    Published on: April 2, 2020

    13.5K
    Author Spotlight: Understanding Disease Mechanisms Through Real-Time Analysis of T-Cell Migration06:42

    Author Spotlight: Understanding Disease Mechanisms Through Real-Time Analysis of T-Cell Migration

    Published on: May 24, 2024

    2.1K

    Related Concept Videos

    Phagocytosis00:41

    Phagocytosis

    Cells pull particles inward and engulf them in spherical vesicles in an energy-requiring process called endocytosis. Phagocytosis ("cellular eating") is one of three major types of endocytosis. Cells use phagocytosis to take in large objects, such as other cells (or their debris), bacteria, and even viruses.
    The objective of phagocytosis is often destruction. Cells use phagocytosis to eliminate unwelcome visitors, like pathogens (e.g., viruses and bacteria). Many immune system cells,...
    6.9K
    Chemotaxis and Direction of Cell Migration01:21

    Chemotaxis and Direction of Cell Migration

    Cells can detect chemical cues in their environment and reorganize the cytoskeleton to migrate toward them or away from them. This directional migration, called chemotaxis, is essential during embryogenesis and development, immune response, tissue repair and regeneration, and reproduction. These chemical cues can either attract or repel the cell's movement. For example, axon development is determined by a combination of chemoattractants and chemorepellents that direct the growing axon...
    5.0K
    Disorders of Leukocytes01:27

    Disorders of Leukocytes

    Leukocyte disorders can lead to either leukopenia, characterized by an abnormally low leukocyte count, or leukocytosis, marked by a very high leukocyte number.
    Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune...
    2.3K
    Immune Surveillance by NK Cells and Phagocytes01:25

    Immune Surveillance by NK Cells and Phagocytes

    Immune surveillance is an integral part of the innate immune system, involving the continuous monitoring of peripheral tissues to detect and respond to pathogens, infected cells, or cancerous cells. This surveillance is conducted primarily by natural killer (NK) cells and phagocytes, which employ distinct but complementary mechanisms to identify and eliminate threats.
    Natural Killer Cells: The Fast Responders
    NK cells are large granular lymphocytes found in the blood and lymphatic system. These...
    7.2K
    Chemotaxis in E. coli01:27

    Chemotaxis in E. coli

    Chemotaxis in Escherichia coli is a sensory-driven motility mechanism that enables bacteria to navigate chemical gradients, moving toward beneficial environments while avoiding harmful conditions. This process relies on a signal transduction system integrating external chemical cues with flagellar motor control.Chemoreceptors and Signal DetectionE. coli detects chemical gradients through methyl-accepting chemotaxis proteins (MCPs), which are membrane-bound chemoreceptors that sense attractants...
    1.4K
    Acute Inflammation I: Cellular Phase01:26

    Acute Inflammation I: Cellular Phase

    The cellular phase of acute inflammation is a tightly orchestrated sequence of events that recruits leukocytes, primarily neutrophils, to sites of tissue injury or infection. Following the initial vascular changes, this phase ensures effective immune cell migration, activation, and function at the affected site to eliminate pathogens and initiate tissue repair.Leukocyte Recruitment CascadeLeukocyte recruitment happens in four steps: margination, adhesion, transmigration, and chemotaxis. Reduced...
    82