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[Transplant pyelonephritis (author's transl)]

V Kym, U Binswanger, J Briner

    Klinische Wochenschrift
    |January 15, 1980
    PubMed
    Summary

    Kidney transplant recipients with chronic urinary tract infections frequently develop transplant pyelonephritis. Early diagnosis using leucocyturia and antibody-coated bacteria is crucial for managing this serious complication.

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    [33 years kidney transplantation in Zurich].

    Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress·1999

    Area of Science:

    • Nephrology
    • Urology
    • Infectious Diseases

    Background:

    • Kidney allograft recipients are susceptible to urinary tract infections (UTIs).
    • Chronic or recurrent UTIs pose a significant risk for post-transplant complications.

    Observation:

    • Significant bacteriuria was detected in 274 of 1,802 urine samples from 216 kidney transplant recipients.
    • Fifteen patients were diagnosed with transplant pyelonephritis, and 11 with cystitis.
    • Predisposing factors included urinary tract obstruction and higher prednisone doses (>10 mg).

    Findings:

    • Persistent leucocyturia and antibody-coated bacteria were key diagnostic indicators for transplant pyelonephritis.
    • Transplant pyelonephritis led to transplant function deterioration in 13 of 15 patients, with two requiring hemodialysis.
    • Septicemia occurred in eight patients with transplant pyelonephritis.

    Implications:

    • Transplant pyelonephritis is a frequent complication in kidney allograft recipients with chronic UTIs.
    • Prompt diagnosis and treatment are essential to preserve kidney transplant function and prevent severe outcomes like septicemia.
    • Identifying predisposing factors like urinary tract obstruction can aid in early intervention strategies.

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