Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Talc retinopathy

S B Murphy, W B Jackson, J A Pare

    Canadian Journal of Ophthalmology. Journal Canadien D'Ophtalmologie
    |July 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Talc particles from intravenous methadone injections can cause retinopathy and severe pulmonary fibrosis in drug abusers. Early detection by ophthalmologists is crucial to prevent debilitating lung complications.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Diseases of captive yellow seahorse Hippocampus kuda Bleeker, pot-bellied seahorse Hippocampus abdominalis Lesson and weedy seadragon Phyllopteryx taeniolatus (Lacépède).

    Journal of fish diseases·2014
    Same author

    Deep fungal dermatitis caused by the Chrysosporium anamorph of Nannizziopsis vriesii in captive coastal bearded dragons (Pogona barbata).

    Australian veterinary journal·2011
    Same author

    Concepts in constitution.

    McGill medical journal·2010
    Same author

    Photothermal spectroscopy of scattering media.

    Applied optics·2010
    Same author

    Photothermal deflection spectroscopy and detection.

    Applied optics·2010
    Same author

    The Physical Status of Men in the Lowest Income Group in the Sixth Decade of Life.

    Canadian Medical Association journal·2010
    Same journal

    Is ophthalmology a pain-free career? A systematic review and meta-analysis of musculoskeletal pain among ophthalmologists.

    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2026
    Same journal

    Evaluation of the Deep Reality Viewer for teaching slit-lamp examination of the anterior segment and the optic nerve head.

    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2026
    Same journal

    Sequential anterior ischaemic optic neuropathy associated with angioid streaks and sphenoid fibrous dysplasia.

    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2026
    Same journal

    Comparative risk of glaucoma surgery in uveitis-associated versus primary open-angle glaucoma: a multicentre database study.

    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2026
    Same journal

    Childhood overweight and obesity as risk factors for astigmatism: a longitudinal analysis.

    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2026
    Same journal

    Stage 1 IRVAN syndrome in an asymptomatic female with BRIP1 mutation.

    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2026
    See all related articles

    Area of Science:

    • Ophthalmology
    • Pulmonology
    • Toxicology

    Background:

    • Intravenous drug abuse, particularly with methadone, poses significant health risks.
    • Oral medications containing talc, when injected intravenously, can lead to systemic complications.
    • Retinopathy and pulmonary fibrosis are potential adverse effects of chronic intravenous talc exposure.

    Purpose of the Study:

    • To investigate the presence of talc particles in the retinal vessels of intravenous methadone users.
    • To correlate talc retinopathy with pulmonary complications in this patient population.
    • To emphasize the role of ophthalmologists in identifying drug abusers and preventing severe outcomes.

    Main Methods:

    • Ophthalmoscopic examination of retinal vessels in patients using intravenous methadone.

    Related Experiment Videos

  • Analysis of patient history regarding the quantity of injected tablets.
  • Review of chest roentgenograms to assess pulmonary changes.

    • Main Results:

    • Talc particles were identified in the retinal vessels of 9 out of 17 intravenous methadone users.
    • Retinopathy was observed in patients who had injected over 9,000 tablets.
    • Seven patients exhibited diffuse micronodular patterns on chest roentgenograms, indicative of progressive pulmonary fibrosis.

    Conclusions:

    • Intravenous injection of oral medications containing talc can lead to talc retinopathy.
    • This retinopathy is associated with severe, disabling pulmonary fibrosis.
    • Ophthalmologists play a key role in the early identification of intravenous drug abusers and in preventing severe pulmonary disease through timely intervention and counseling.