Combined tinidazole and doxycycline short term chemotherapeutic prophylaxis in gastro-intestinal surgery

Infectious complications following gastro-intestinal surgery can be reduced with properly administered antimicrobial agents. One single preoperative dose of doxycyline (200 mg) and tinidazole (2 g) gave a highly significant reduction of infectious complications in a controlled clinical study of 307 patients undergoing elective gastro-intestinal surgery.