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Updated: Jun 29, 2026
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Isolation and Purification of Murine Cardiac Pericytes
Published on: August 16, 2019
PGF2 alpha stimulates release of PGE2 and PGI2 in the isolated perfused rat heart
Advances in Prostaglandin and Thromboxane Research
|January 1, 1980
Abstract:
The effect of prostaglandin F2 alpha on the release of PGI2 and PGE2 was investigated in isolated perfused rat heart. PGF2 alpha at concentrations of 1.7 nmoles liter-1 or higher increased the release of PGI2 and PGE2 alpha. The release of PGI2 was highest after 3 to 4 min of perfusion with PGF2 alpha. This phenomenon may be of physiological significance and might explain the observed variable effects of PGF2 alpha on vascular resistance.
