High mobility group proteins of Saccharomyces cerevisiae

The yeast Saccharomyces cerevisiae contains four proteins having amino acid compositions typical of the high mobility group (HMG) proteins. Three of these are eluted from chromatin by 0.35 M NaCl; one is not, but it is eluted by 0.25 N HCl. It follows that HMGs cannot, in general, be defined by extractability criteria. Gel mobilities and amino acid compositions indicate that yeast and animal HMGs have diverged markedly.