Brief review. Hypertension and the heart
Related Experiment Video
Updated: Oct 1, 2026

Assessing Murine Resistance Artery Function Using Pressure Myography
Published on: June 7, 2013
Insights
Hypertension is a cardiovascular disease, but current methods inadequately assess cardiac function. New approaches are needed to understand the heart's role in hypertension and improve patient care.
Area of Science:
- Cardiology
- Hypertension Research
- Hemodynamics
Background:
- Hypertension is recognized as a cardiovascular disease.
- Early hemodynamic methods were used in hypertensive patients.
- Current understanding of the heart's role in hypertension is limited.
Purpose of the Study:
- To highlight the limitations of current methods in characterizing cardiac function in hypertension.
- To emphasize the need for improved diagnostic tools for hypertensive patients.
Main Methods:
- Review of existing epidemiologic and hemodynamic studies.
- Discussion of the inadequacy of peripheral hemodynamic parameter measurements.
- Evaluation of invasive and noninvasive methods for cardiac function assessment.
Main Results:
- Peripheral hemodynamic measurements are insufficient for characterizing cardiac function in hypertension.
- Invasive methods are limited to specific diagnostic scenarios like preoperative coronary heart disease assessment.
- Traditional noninvasive methods (phonocardiography, sphygmography, apex cardiography) have limited utility in assessing cardiac function in hypertension.
Conclusions:
- Existing methods for assessing cardiac function in hypertension are inadequate.
- Further research and development of advanced diagnostic techniques are necessary.
- Improved characterization of cardiac function is crucial for managing hypertension effectively.
Abstract:
Epidemiologic studies led cardiologists to consider hypertension as a cardiovascular disease although hemodynamic methods developed in the early 1940s were in some cases already used with hypertensive patients (Fejifar and Fejifarova, 1961). Present knowledge of the role of the heart in hypertension is limited because the methods of measuring the more "peripheral" hemodynamic parameters, such as cardiac output, heart work, total blood volume, or resistance, are inadequate for characterization of cardiac function. An extensive application of invasive methods, however, may only be taken into consideration if, for instance, a preoperative diagnosis of coronary heart disease must be made at the same time. In addition, noninvasive methods such as phonocardiography, carotid sphygmography, conventional apex cardiography, and similar methods which were the only techniques available in the past, are of little use in the characterization of cardiac function and in hypertension.
Related Concept Videos
Blood Pressure
The average BP in an adult is typically around 120/80 mmHg (millimeters of mercury). In this measurement, the numerator (120) indicates the systolic pressure, which is the pressure in the arteries during the contraction of the heart's ventricles as blood is expelled. The denominator (80) represents the diastolic...
Disorders of the Autonomic Nervous System
Raynaud's disease, also known as Raynaud's phenomenon, is a...
Hypertension and Regulation of Blood Pressure
Hypertension I: Introduction
Hypertension II: Pathophysiology
Hypertension III: Clinical Manifestations and Diagnostic Studies

