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Related Experiment Videos

Phase variation in the genus Serratia

V M Young, M R Moody, M J Morris

    Journal of Medical Microbiology
    |May 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Serratia marcescens strains in a cancer center exhibited multiple H antigens, with some strains showing diphasic or triphasic antigen expression. This is the first report of such complex H antigen phases in this bacterial genus.

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    Area of Science:

    • Microbiology
    • Bacteriology
    • Immunology

    Background:

    • Serratia marcescens is an opportunistic pathogen.
    • Understanding bacterial serotypes is crucial for infection control.
    • H antigens are important for bacterial classification and identification.

    Purpose of the Study:

    • To investigate the H antigen serotypes of Serratia marcescens in a cancer center.
    • To identify and characterize strains with multiple H antigens.

    Main Methods:

    • Serotyping of 241 Serratia marcescens strains.
    • Analysis of H antigen expression, including diphasic and triphasic patterns.

    Main Results:

    • 8.7% of strains displayed more than one H antigen.

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  • 19 diphasic and 2 triphasic strains were identified.
  • H antigen 1 was present in approximately half of the multi-phasic strains.

    • Conclusions:

    • This study reports the first observation of multiple H antigen phases in the genus Serratia.
    • The findings highlight the antigenic diversity within Serratia marcescens.
    • Further research is needed to understand the implications of these findings for diagnostics and epidemiology.