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Preparation of Primary Acute Lymphoblastic Leukemia Cells in Different Cell Cycle Phases by Centrifugal Elutriation
Published on: November 10, 2017
Abstract:
A review is presented of the available data in the medical literature and of the author's experience in the study of leukocyte kinetics, starting with the originary stem cell. To facilitate understanding of the process of leukocyte proliferation in leukemias, theoretical and methodological details are given on the techniques for determination of the cell cycle and its perturbations during evolution of the various types of leukemias. Some data on animal leukemias are also discussed. A critical analysis is made of the action of immunosuppressive cytostatic drugs on the leukemic cell proliferation.
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