Related Experiment Video
Updated: Aug 17, 2026

Myo-mechanical Analysis of Isolated Skeletal Muscle
Published on: February 23, 2011
Changes in the contractile proteins of skeletal muscles induced by steroid myopathy
Abstract:
The effect of chronic dexamethasone treatment was investigated on the myofibriller proteins of slow (soleus) and fast (semimembranous) muscles. The relative quantities of actin, protein C and protein M increased, while the myosin, troponin inhibitor and calcium binding components showed a relative decrease in both muscle types. The amount of troponin regulatory component and alpha-actinin decreased only in the fast muscle, while tropomyosin decreased significantly in the slow muscle. The isoenzyme pattern of fast muscle myosin was altered as a consequence of decreased myosin (LC-3 subunit.
Related Concept Videos
Muscle Contraction
Actin and Myosin in Muscle Contraction
Muscle Contraction
Disorders of the Skeletal Muscle
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
Smooth Muscle Contraction
The onset of contraction is triggered by an increase in calcium ions within the sarcoplasm, similar to the process in striated muscle. However, smooth muscles have a relatively smaller reservoir of the sarcoplasmic...
Alterations in Muscle Tone lll

