Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Vaginal agenesis

F F Marshall

    Clinics in Plastic Surgery
    |April 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Mesonephric duct anomalies can cause vaginal agenesis, leading to primary amenorrhea in females with normal hormonal function. Surgical reconstruction using split-thickness skin grafts offers successful long-term outcomes for vaginal agenesis.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Intratumor C-reactive protein as a biomarker of prognosis in localized renal cell carcinoma.

    The Journal of urology·2011
    Same author

    EPLIN downregulation promotes epithelial-mesenchymal transition in prostate cancer cells and correlates with clinical lymph node metastasis.

    Oncogene·2011
    Same author

    Postoperative better than preoperative C-reactive protein at predicting outcome after potentially curative nephrectomy for renal cell carcinoma.

    Urology·2010
    Same author

    Absolute preoperative C-reactive protein predicts metastasis and mortality in the first year following potentially curative nephrectomy for clear cell renal cell carcinoma.

    The Journal of urology·2009
    Same author

    cAMP-responsive element-binding protein regulates vascular endothelial growth factor expression: implication in human prostate cancer bone metastasis.

    Oncogene·2007
    Same author

    Surgery in advanced and metastatic renal cell carcinoma.

    Current opinion in urology·2006
    Same journal

    Lower-Extremity Reconstruction: Principles, Progress, and Perspectives.

    Clinics in plastic surgery·2026
    Same journal

    Pediatric.

    Clinics in plastic surgery·2026
    Same journal

    Lower Extremity Reconstruction in Acute Burns.

    Clinics in plastic surgery·2026
    Same journal

    Chronic Lower Extremity Wounds: Updates on Lower Extremity Reconstruction in Clinics in Plastic Surgery.

    Clinics in plastic surgery·2026
    Same journal

    Updates in Lower Extremity Reconstruction: Post Sarcoma.

    Clinics in plastic surgery·2026
    Same journal

    Fillet Flaps for Lower Extremity Salvage.

    Clinics in plastic surgery·2026
    See all related articles

    Area of Science:

    • Reproductive medicine
    • Embryology
    • Surgical innovation

    Background:

    • Normal vaginal development relies on the mesonephric duct, paramesonephric duct, and urogenital sinus.
    • Mesonephric anomalies are implicated in vaginal agenesis and related genitourinary abnormalities.
    • Patients typically present with primary amenorrhea, normal female phenotype, karyotype, and hormonal function.

    Purpose of the Study:

    • To investigate the developmental origins of vaginal agenesis.
    • To review the clinical presentation and management of patients with vaginal agenesis.
    • To evaluate the efficacy of surgical reconstruction techniques.

    Main Methods:

    • Review of embryological development of the female reproductive tract.
    • Analysis of clinical case data for patients with vaginal agenesis.

    Related Experiment Videos

  • Assessment of surgical outcomes for vaginal reconstruction procedures.

    • Main Results:

    • Mesonephric duct anomalies are a key factor in the etiology of vaginal agenesis.
    • Associated genitourinary abnormalities frequently accompany vaginal agenesis.
    • Split-thickness skin grafting is a common and effective method for vaginal reconstruction.

    Conclusions:

    • Understanding the embryological basis of vaginal agenesis is crucial for diagnosis.
    • Management involves addressing both vaginal agenesis and concurrent genitourinary issues.
    • Split-thickness skin grafting provides a reliable surgical solution for vaginal agenesis with positive long-term results.