Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Lymphocyte maldistribution and immunodeficiency

M de Sousa

    Hospital Practice
    |July 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Lymphocytopenias, or low lymphocyte counts, may not indicate cell loss but rather sequestration in lymphoid tissues. This study investigates the clinical significance of such lymphocyte imbalances in various diseases.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The "Football is Medicine" platform-scientific evidence, large-scale implementation of evidence-based concepts and future perspectives.

    Scandinavian journal of medicine & science in sports·2018
    Same author

    [Not Available].

    Immunology today·2014
    Same author

    Immunoregulation by iron-binding proteins.

    Immunology today·2014
    Same author

    Silent Burdens in Disease: Fatigue and Depression in SLE.

    Autoimmune diseases·2014
    Same author

    Cognitive exposure versus avoidance in patients with chronic pain: adherence matters.

    European journal of pain (London, England)·2013
    Same author

    The unfolded protein response in hereditary haemochromatosis.

    Journal of cellular and molecular medicine·2007
    Same journal

    Cri du chat and Potter syndromes: a decision to abort.

    Hospital practice·1992
    Same journal

    Who decides when care is futile?

    Hospital practice·1991
    Same journal

    Withholding and withdrawing life support.

    Hospital practice·1991
    Same journal

    Of dead brains, living wills, and autonomy.

    Hospital practice·1991
    Same journal

    Partner notification for HIV control.

    Hospital practice·1990
    Same journal

    Promiscuity and public health: some clinical and ethical issues.

    Hospital practice·1990
    See all related articles

    Area of Science:

    • Hematology
    • Immunology
    • Pathophysiology

    Background:

    • Lymphocytopenias are commonly observed in clinical practice.
    • Unlike other blood cell deficiencies, lymphocytopenias may not represent a true reduction in lymphocyte numbers.

    Purpose of the Study:

    • To explore the concept that lymphocytopenias can result from lymphocyte sequestration in lymphatic tissues.
    • To investigate the clinical significance of these lymphocyte imbalances in various disease states.

    Main Methods:

    • Review of existing literature on lymphocyte kinetics.
    • Analysis of patient data correlating lymphocytopenia with disease outcomes.
    • Exploration of the dynamic interchange between blood and lymphoid circulation.

    Main Results:

    Related Experiment Videos

    • Absence of lymphocytes from peripheral blood often signifies their redistribution to lymphoid organs.
    • This sequestration can be a critical factor in the pathophysiology of certain diseases.

    Conclusions:

    • Lymphocytopenias require careful interpretation, considering potential sequestration rather than depletion.
    • Understanding lymphocyte trafficking is crucial for diagnosing and managing diseases associated with low lymphocyte counts.