Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Genetic patterns in diabetes mellitus

R Tattersall, D Pyke, J Nerup

    Human Pathology
    |May 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Recent advances distinguish genetic differences between insulin-dependent and insulin-independent diabetes. Research is progressing on insulin-dependent diabetes causes and inheritance, while insulin-independent diabetes remains largely unraveled.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Respiratory measurements and airway clearance device prescription over one year in amyotrophic lateral sclerosis.

    Amyotrophic lateral sclerosis & frontotemporal degeneration·2019
    Same author

    Genetic markers for glutamic acid decarboxylase do not predict insulin-dependent diabetes mellitus in pairs of affected siblings.

    Human genetics·2016
    Same author

    Confirmation of novel type 1 diabetes risk loci in families.

    Diabetologia·2012
    Same author

    HbA₁(c) and mean blood glucose show stronger associations with cardiovascular disease risk factors than do postprandial glycaemia or glucose variability in persons with diabetes: the A1C-Derived Average Glucose (ADAG) study.

    Diabetologia·2010
    Same author

    Real-life glycaemic profiles in non-diabetic individuals with low fasting glucose and normal HbA1c: the A1C-Derived Average Glucose (ADAG) study.

    Diabetologia·2010
    Same author

    Germany [medical supplies].

    Lancet (London, England)·2010
    Same journal

    TRPS1 and GATA3 Expression in BRG1/SMARCA4-deficient Malignant Neoplasms.

    Human pathology·2026
    Same journal

    Clinicopathologic and Molecular Characteristics of Acral Melanomas Harboring RARA Fusions.

    Human pathology·2026
    Same journal

    Clinical Impact of Second Opinion Consultation in Bladder Biopsies and Transurethral Resection of Bladder Tumors.

    Human pathology·2026
    Same journal

    Prognostic relevance and molecular correlates of Claudin-1 expression in pancreatic neuroendocrine tumors.

    Human pathology·2026
    Same journal

    Mixed Phenotype Acute Leukemia: Lineage Assignment, Immunophenotypic Classification and Genetic Insights.

    Human pathology·2026
    Same journal

    Chronic myelomonocytic leukemia revisited: A comprehensive review with emphasis on the oligomonocytic subtype.

    Human pathology·2026
    See all related articles

    Area of Science:

    • Endocrinology and Genetics
    • Metabolic Diseases Research

    Background:

    • Diabetes mellitus encompasses diverse syndromes characterized by hyperglycemia.
    • Etiologies range from purely genetic to non-genetic factors.
    • Recent evidence differentiates the genetic basis of insulin-dependent diabetes (IDDM) from insulin-independent diabetes (IIDM).

    Purpose of the Study:

    • To highlight the progress in understanding the genetic underpinnings of different diabetes types.
    • To underscore the challenges in elucidating the etiology and inheritance of IIDM.

    Main Methods:

    • Review of recent genetic and epidemiological studies on diabetes.
    • Comparative analysis of etiological factors in IDDM and IIDM.

    Main Results:

    Related Experiment Videos

    • Significant advancements in identifying genetic factors for IDDM.
    • IDDM appears to involve genetic susceptibility interacting with environmental triggers.
    • Limited progress in understanding the complex etiologies and inheritance patterns of IIDM.

    Conclusions:

    • The genetic landscape of diabetes is complex and type-specific.
    • Further research is crucial for unraveling the multifactorial causes of IIDM.
    • Understanding genetic susceptibility and environmental interactions is key for IDDM research.