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Diabetic heart disease

A C Asmal, W P Leary, F Thandroyen

    South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
    |May 10, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Heart disease in diabetics is complex, not solely coronary atherosclerosis. It involves a mix of coronary atheroma, cardiomyopathy, micro-angiopathy, and autonomic neuropathy, contributing to excess mortality.

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    Area of Science:

    • Cardiology
    • Diabetology
    • Pathophysiology

    Background:

    • Diabetes mellitus is associated with increased mortality from heart disease.
    • Coronary atherosclerosis is often presumed to be the primary cause of this excess mortality.
    • However, shared risk factors between diabetes and coronary atherosclerosis complicate this assumption.

    Purpose of the Study:

    • To investigate the multifaceted nature of heart disease in diabetic patients.
    • To differentiate heart disease in diabetes from traditional coronary heart disease.
    • To identify the various pathological components contributing to cardiac mortality in diabetes.

    Main Methods:

    • Review of existing evidence on heart disease in diabetes.
    • Comparative analysis of risk factors for coronary atherosclerosis in diabetic and non-diabetic populations.

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  • Examination of pathological findings in diabetic cardiac mortality.

    • Main Results:

    • Heart disease in diabetes is not solely attributable to coronary atherosclerosis.
    • Diabetic heart disease encompasses a combination of pathologies.
    • These include coronary atheroma, cardiomyopathy, micro-angiopathy, and autonomic neuropathy.

    Conclusions:

    • Heart disease in diabetes is a complex condition with diverse underlying mechanisms.
    • It is crucial to recognize the distinct pathological entities beyond coronary atherosclerosis.
    • Understanding these components is vital for accurate diagnosis and management of cardiac complications in diabetes.