[Changes of insulin secretion in obese children on 2 different diets]

In this work, we studied a group of obese children submitted to two different types of diet (ketogenic and hypocaloric) for 8 weeks and the relationship with liberation of insulin by beta cells of Langerhans islands. It was shown that in children under ketogenic diet, the drop in weight, together with the liberation of insulin, was significantly greater than in those given hypocaloric diet. The possible role of gastrointestinal hormones and opther factors related with the diet are evaluated. It is concluded that the greater reduction in body weight in patients given ketogenic diet is an important factor in the normalization of plasmatic insulin levels.