[Successful bone-marrow transplantation after eleven years (author's transl)]

Bone-marrow transplantation for severe aplastic anaemia was performed in a 14-year-old boy in 1969. The transplanted marrow was not HLA identical: there was HLA-D incompatibility between the female donor and the recipient. The patient had had several blood transfusions and one course of cytostatic conditioning before the transplantation. Six years later he had carcinoma of the colon which was completely removed at surgery. Ten years after transplantation, chimaerism was demonstrated in the recipient who was then haematologically and clinically healthy and in full employment. The bone-marrow transplantation can thus be considered as successful.