Heterogeneity of plasma IRI responses in patients in IGT and diabetes

Genotype/phenotype relationships in HNF-4alpha/MODY1: haploinsufficiency is associated with reduced apolipoprotein (AII), apolipoprotein (CIII), lipoprotein(a), and triglyceride levels.

Diabetes·2000

Reduced pancreatic polypeptide response to hypoglycemia and amylin response to arginine in subjects with a mutation in the HNF-4alpha/MODY1 gene.

Diabetes·2000

Diminished insulin and glucagon secretory responses to arginine in nondiabetic subjects with a mutation in the hepatocyte nuclear factor-4alpha/MODY1 gene.

Diabetes·1997

Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)

Nature·1996

Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)

Nature·1996

Altered insulin secretory responses to glucose in diabetic and nondiabetic subjects with mutations in the diabetes susceptibility gene MODY3 on chromosome 12.

Diabetes·1996

CCKBR signalling controls human definitive endoderm specification and pancreatic lineage differentiation.

Diabetologia·2026

Renal tubule-specific Nrf2 deletion ameliorates diabetic kidney disease by attenuating glomerular hypertension and kidney injury in a mouse model of diabetes.

Diabetologia·2026

Prediabetes subtype-based stratification reveals distinct long-term risks for type 2 diabetes.

Diabetologia·2026

Evolving phenotype of newly diagnosed type 2 diabetes: a 15-year population-based comparison.

Diabetologia·2026

Altered glucagon and GIP responses in South Asian versus Nordic women after gestational diabetes mellitus.

Diabetologia·2026

Efficacy and safety of HRS-7535, a novel oral small-molecule glucagon-like peptide-1 receptor agonist, in participants with type 2 diabetes mellitus inadequately controlled by metformin and sodium-glucose co-transporter 2 inhibitors: a multicentre, randomised, double-blind, placebo-controlled, parallel-group Phase II trial.

Diabetologia·2026

An IL-21R STAT hypomorph circumvents functional redundancy in germinal centre responses.

eLife·2026

A narrative review of stem cell-based therapy for fibrosing interstitial lung diseases: clinical evidence and translational perspectives.

Frontiers in pharmacology·2026

Clinicopathologic characteristics and diagnostic value of PD-L1 in immune checkpoint inhibitor-related liver injury: a single-center retrospective study.

Frontiers in oncology·2026

Kidney biopsy in the diagnosis of immunoglobulin A nephropathy.

Frontiers in medicine·2026

The Largest Cohort Study of Intravenous Leiomyomatosis Reveals HMGA2 and Collagen Gene Alterations as Cooperative Drivers.

The American journal of surgical pathology·2026

An interferonopathy associated with a monoallelic variant in TRIM28.

Pediatric rheumatology online journal·2026

Related Experiment Videos

Heterogeneity of plasma IRI responses in patients in IGT and diabetes

Related Concept Videos

Genotype/phenotype relationships in HNF-4alpha/MODY1: haploinsufficiency is associated with reduced apolipoprotein (AII), apolipoprotein (CIII), lipoprotein(a), and triglyceride levels.

Reduced pancreatic polypeptide response to hypoglycemia and amylin response to arginine in subjects with a mutation in the HNF-4alpha/MODY1 gene.

Diminished insulin and glucagon secretory responses to arginine in nondiabetic subjects with a mutation in the hepatocyte nuclear factor-4alpha/MODY1 gene.

Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)

Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)

Altered insulin secretory responses to glucose in diabetic and nondiabetic subjects with mutations in the diabetes susceptibility gene MODY3 on chromosome 12.

CCKBR signalling controls human definitive endoderm specification and pancreatic lineage differentiation.

Renal tubule-specific Nrf2 deletion ameliorates diabetic kidney disease by attenuating glomerular hypertension and kidney injury in a mouse model of diabetes.

Prediabetes subtype-based stratification reveals distinct long-term risks for type 2 diabetes.

Evolving phenotype of newly diagnosed type 2 diabetes: a 15-year population-based comparison.

Altered glucagon and GIP responses in South Asian versus Nordic women after gestational diabetes mellitus.

An IL-21R STAT hypomorph circumvents functional redundancy in germinal centre responses.

A narrative review of stem cell-based therapy for fibrosing interstitial lung diseases: clinical evidence and translational perspectives.

Clinicopathologic characteristics and diagnostic value of PD-L1 in immune checkpoint inhibitor-related liver injury: a single-center retrospective study.

Kidney biopsy in the diagnosis of immunoglobulin A nephropathy.

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An interferonopathy associated with a monoallelic variant in TRIM28.

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Heterogeneity of plasma IRI responses in patients in IGT and diabetes

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