Developmental profile of enzyme activity in several tissues of the C57BL/6 mouse between birth and 35 days of age

The activity of 19 liver enzymes as well as the level of activity of a lesser number of enzymes in brain, kidney and heart tissue was measured in C57BL/6 mice at various ages between birth and 35 days. Several enzymes were present at significant levels in the liver at earlier ages than reported for rat liver. The time course of the development, the magnitude of the charges and the direction of the changes are often significantly different from the profiles observed in rat tissues, thus the mouse may respond differently than other species to dietary alterations and/or hormonal stimulations during the developmental period.