[Antigenic translocation of carcinoembryonic antigen in large intestine epithelial cells]

By an indirect Coons test, a carcinoembryonic antigen (CEA) localization was studied in cells of colon mucosa at various stages of human embryonic development, polyps, and in cases of non-tumoral changes. Laboratory investigations have shown that there are several variants of CEA localization in embryogeny, precancerous tissue, and in cells with inflammatory changes. A comparison of the obtained data and forms of antigenic translocation in malignant tissue leads to a conclusion that the antigenic translocation phenomenon is of biological nature, reflecting the degree of changes in the inner structure of cells under various conditions of existence.