Flurbiprofen in the management of dysmenorrhoea

The analgesic effect of flurbiprofen, aspirin and placebo in the treatment of primary dysmenorrhoea was compared in 41 patients using a double blind triple crossover study. No statistically significant differences were found between any pair of treatments and the control for pain relief. Thirty patients had assessments for all three treatment months, 11 preferred flurbiprofen, 9 preferred placebo, 6 preferred aspirin and 4 had no preference between any of the treatments. Side effects were reported by 14 of the 41 patients: 3 during the control month, 6 during the flurbiprofen month, 4 during the aspirin month and 7 during the placebo month.