Related Experiment Video
Updated: Aug 11, 2026

09:42
A Chronic Autoimmune Dry Eye Rat Model with Increase in Effector Memory T Cells in Eyeball Tissue
Published on: June 7, 2017
Abstract:
Induction of autoimmunity in the rat lacrimal gland was presently assessed. Antibodies to lacrimal gland extract were detectable in 58% of the immunized rats. Skin tests were positive at 4 week postimmunization in 70% of the animals. Histological observations revealed the presence of mononuclear cell infiltrates surrounding the ductal and acinar epithelium at 2--6 weeks.

