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Magnesium metabolism: a review

H Ebel, T Günther

    Journal of Clinical Chemistry and Clinical Biochemistry. Zeitschrift Fur Klinische Chemie Und Klinische Biochemie
    |May 1, 1980
    PubMed
    Summary

    This review covers magnesium's physiology, biochemistry, and related disorders. It details magnesium's distribution, absorption, hormonal regulation, and the effects of low (hypomagnesemia) and high (hypermagnesemia) levels.

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    Area of Science:

    • Biochemistry
    • Physiology
    • Pathophysiology

    Background:

    • Magnesium is a vital element with complex physiological and biochemical roles.
    • Understanding magnesium's distribution and regulation is crucial for clinical practice.

    Purpose of the Study:

    • To comprehensively review the literature on magnesium.
    • To cover magnesium's physiology, biochemistry, pathophysiology, and pathobiochemistry.

    Main Methods:

    • Literature review of existing studies on magnesium.
    • Synthesis of information on magnesium distribution, transport, and regulation.

    Main Results:

    • Detailed examination of magnesium's physico-chemical state in various body compartments.
    • Explanation of intestinal absorption, renal excretion, and hormonal regulation of magnesium.
    • Discussion of the biochemical mechanisms and clinical effects of magnesium imbalances (hypomagnesemia and hypermagnesemia).

    Conclusions:

    • Magnesium homeostasis is tightly regulated by complex physiological and hormonal mechanisms.
    • Disruptions in magnesium levels can lead to significant clinical disturbances.
    • This review provides a foundational understanding of magnesium's role in health and disease.

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