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Saccharomyces cerevisiae septicemia

M L Eschete, B C West

Archives of Internal Medicine

|November 1, 1980

Summary

This summary is machine-generated.

This study details a rare case of bloodstream infection (septicemia) caused by Saccharomyces cerevisiae in a hospitalized burn patient. The yeast, typically harmless, became pathogenic due to the patient's weakened state, highlighting a rare clinical presentation.

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Area of Science:

Medical Mycology
Infectious Diseases
Clinical Microbiology

Background:

Saccharomyces cerevisiae, a common yeast, is generally considered non-pathogenic.
Opportunistic infections can occur in immunocompromised or debilitated individuals.
Nosocomial infections pose a significant challenge in healthcare settings.

Observation:

A rare case of Saccharomyces cerevisiae septicemia was observed in a hyperalimented burn patient.
The infection appeared to originate from a bleeding esophageal lesion.
The patient presented with severe neutropenia, thrombocytopenia, hypothermia, and monocytopenia.

Findings:

This is the first reported instance of septicemia caused by Saccharomyces cerevisiae.
The yeast acted as an opportunistic pathogen in a debilitated host.

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Clinical manifestations included profound cytopenias and hypothermia.

Implications:

Highlights the potential pathogenicity of Saccharomyces cerevisiae in susceptible individuals.
Emphasizes the importance of considering unusual pathogens in nosocomial infections.
Amphotericin B demonstrated efficacy in treating this rare yeast septicemia.