[Adjuvant chemotherapy in the conception of multimodal cancer treatment (author's transl)]

Without any doubt remarkable progress in the field of adjuvant cancer chemotherapy after local-regional treatment has been achieved during the last decade. Nevertheless the real results are behind our expectations basing on theoretical and experimental considerations. Therefore adjuvant cancer chemotherapy should be used only within controlled clinical trials. Routine application of surgical adjuvant chemotherapy or combined radiological and cytostatic treatment in localized tumours can not be recommended.