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[Penetrating keratoplasties (author's transl)]
Journal Francais D'Ophtalmologie
|January 1, 1980
Summary
Specular microscopy of 19 penetrating keratoplasties, seven with intra-ocular lenses, revealed similar endothelial cell density. Graft clarity was maintained even with low cell counts, suggesting good long-term outcomes.
Area of Science:
- Ophthalmology
- Corneal Surgery
- Cell Biology
Context:
- Specular microscopy is crucial for assessing corneal endothelial health.
- Penetrating keratoplasty (corneal transplant) outcomes are influenced by endothelial cell density.
- Intra-ocular lenses (IOLs) are sometimes implanted concurrently with corneal transplants.
Purpose:
- To evaluate endothelial cell density and graft survival in penetrating keratoplasty.
- To compare corneal endothelial cell density in grafts with and without intra-ocular lenses.
- To assess the relationship between cell density and graft clarity post-transplant.
Summary:
- This study analyzed 19 penetrating keratoplasty cases using specular microscopy.
- Seven of these grafts were performed with an intra-ocular lens.
- The mean endothelial cell density was 1,100 cells/mm², with no significant difference between the groups with or without IOLs.
- One graft remained clear with a cell density as low as 330 cells/mm².
Impact:
- Findings suggest that corneal grafts can maintain clarity and function even with reduced endothelial cell density.
- The presence of an intra-ocular lens does not appear to negatively impact endothelial cell density post-keratoplasty.
- This research provides valuable insights into the long-term prognosis of corneal transplantation.