[Heterogeneity of the methanol-assimilating yeasts Candida boidinii with respect to alcohol oxidase content]

The activity of alcohol oxidase (AO) in the cells of Candida boidinii, in actively growing cultures, depends on the stage of the cell cycle. The minimal activity of AO was found in young cells produced by budding and in cells in the process of budding. The maximal activity of AO was detected in the fraction of cells of a medium size. The activity of AO decreased abruptly when the cells proceeded to budding. The activity of catalase depended on the stage of the cell cycle only to a minor extent.