Related Experiment Video
Updated: Aug 8, 2026

Mixed Primary Cultures of Murine Small Intestine Intended for the Study of Gut Hormone Secretion and Live Cell Imaging of Enteroendocrine Cells
Published on: April 20, 2017
The relationship of gastric acid secretion to plasma glucose in five men
Abstract:
Twelve-hour basal gastric acid collection (no. = 113) and insulin-stimulated acid studies (no. = 47) were obtained in five healthy male volunteers. Basal collections were obtained during infusion with intravenous saline, 5% glucose, or 15% glucose solutions. Various insulin dosages were used for the insulin studies. Thus, for each subject a hyperglycemic to hypoglycemic plasma glucose range was produced which could be related to acid output. In the normoglycemic range (110 to 57 mg/100 ml) a graded acid increase was noted in association with a graded reduction in plasma glucose. This suggests that physiological variations in plasma glucose influence acid secretion in man.
Related Concept Videos
Stomach pH Regulation
The acid-secreting gastric mucosal epithelial cells (parietal cells) lining the stomach lumen maintain the low pH in the lumen. Numerous ion transporters and channels on these parietal...
Hormones Regulating Blood Glucose
In addition to accelerating glucose uptake and utilization, insulin has...
Gastric Phase of Digestion
When food enters the stomach, it stretches the stomach walls and activates stretch receptors. This triggers local reflexes of the enteric nervous system, mediated through the myenteric plexus. These...
Glucose Homeostasis: Regulation of Blood Glucose
During fasting, when blood glucose levels are low, the pancreas secretes glucagon. it...
Glucose Homeostasis: Pancreatic Islets and Insulin Secretion
Insulin and C-peptide are co-secreted in...
Hypoglycemia and Glucagon

