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Yersinia pseudotuberculosis infection in a group of Macaca fascicularis
Abstract:
Diarrheal disease associated with abortions and stillbirths occurred in a group of 42 Macaca fascicularis. The group was composed of wild-caught adults and their colony-born offspring housed in a half-acre cage. Thirteen adult females and 1 infant male were affected. All 14 monkeys had diarrhea and all 9 pregnant females either aborted or had a stillbirth. Yersinia pseudotuberculosis was isolated from 7 animals. In addition, Y enterocolitica was isolated from 1 monkey and Shigella flexneri type IV was isolated from 5 monkeys. One adult female had a mixed infection of both Y pseudotuberculosis and S flexneri. Every pregnant monkey from which Y pseudotuberculosis was isolated aborted or had a stillbirth. Five animals died, and Y pseudotuberculosis was the only pathogen isolated from these 5 monkeys.
Insights
Diarrheal disease in cynomolgus macaques was linked to abortions and stillbirths. Yersinia pseudotuberculosis was a key pathogen, especially in pregnant females, causing pregnancy loss and death.
Area of Science:
- Veterinary Medicine
- Primate Health
- Infectious Diseases
Background:
- Diarrheal diseases pose significant threats to captive primate populations.
- Reproductive complications like abortions and stillbirths can indicate underlying infectious agents.