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Published on: October 22, 2013
Significance of enteric gram-negative bacilli in the throat
Abstract:
Pharyngeal micro-organisms of 131 Australian and Malaysian children and adults were compared by analysis of aerobic culture of throat swab specimens. Enteric Gram-negative bacilli were commonly isolated in small numbers from Malaysian adults whether they had sore throats (28%) or not (36%), but were detected in only 9% of Australian adults without sore throats and in only 12% and 4% of Malaysian children with and without sore throats respectively. In other respects microbiological findings were similar in the different groups of subjects studied. It is concluded that the pharyngeal carriage rate of enteric Gram-negative bacilli may differ substantially between different groups of normal individuals. Our findings also suggest that these micro-organisms do not have a pathogenic role in pharyngitis.
Insights
Enteric Gram-negative bacilli are commonly found in the throats of Malaysian adults, but rarely in Australians. These microbes do not appear to cause pharyngitis (sore throat).
Area of Science:
- Microbiology
- Public Health
Background:
- Pharyngeal micro-organisms play a role in upper respiratory health.
- Understanding microbial carriage in different populations is crucial for public health.
Purpose of the Study:
- To compare pharyngeal micro-organisms between Australian and Malaysian children and adults.
- To investigate the prevalence of enteric Gram-negative bacilli in the pharynx.
Main Methods:
- Aerobic culture of throat swab specimens from 131 Australian and Malaysian subjects.
- Comparative analysis of microbial isolation rates across different demographic groups.
Main Results:
- Enteric Gram-negative bacilli were frequently isolated from Malaysian adults (28-36%) but rarely from Australian adults (9%).
- Prevalence in Malaysian children was 12% (with sore throat) and 4% (without sore throat).
- Microbiological findings were otherwise similar across groups.
Conclusions:
- Pharyngeal carriage rates of enteric Gram-negative bacilli vary significantly between populations.
- These bacilli likely do not play a pathogenic role in pharyngitis.
Related Concept Videos
Acute Pharyngitis
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Chronic Pharyngitis
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
The Oral Microbiota
Microbiota of the Respiratory Tract
Microbiota of the Stomach and Small Intestine
Streptococcal Pharyngitis

