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Candidiasis of the duodenum and jejunum
Gastroenterology
|April 1, 1981
Summary
Diagnosing small bowel Candida infection antemortem is challenging. This case report highlights radiologic and endoscopic findings that enabled successful diagnosis and treatment in a renal transplant patient.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Transplant Medicine
Background:
- Gastrointestinal candidiasis, particularly small bowel infection, is frequently observed post-mortem (up to 20% of cases).
- Antemortem diagnosis of small bowel candidiasis has historically been difficult and rarely reported.
Observation:
- A renal transplant recipient presented with symptoms suggestive of upper gastrointestinal candidiasis.
- The patient exhibited candidiasis in the esophagus, duodenum, and jejunum.
Findings:
- Radiologic and endoscopic examinations were crucial in suggesting the correct antemortem diagnosis of small bowel involvement.
- These diagnostic modalities identified esophageal, duodenal, and jejunal candidiasis.
Implications:
- This case demonstrates the feasibility of antemortem diagnosis for small bowel candidiasis.
- Successful antifungal therapy led to complete resolution of the observed gastrointestinal candidiasis findings.
- Early diagnosis and treatment can improve outcomes for immunocompromised patients with invasive fungal infections.
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