Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Vesicular pemphigoid

G G Gruber, L G Owen, J P Callen

    Journal of the American Academy of Dermatology
    |December 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    This study describes a patient with a rare vesicular variant of bullous pemphigoid (BP) that initially mimicked dermatitis herpetiformis (DH). The patient required methotrexate alongside corticosteroids for effective lesion management, highlighting a unique treatment challenge in BP variants.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Anti-C1q antibodies in systemic lupus erythematosus.

    Lupus·2014
    Same author

    Hypertrophic lupus erythematosus complicating long-standing systemic lupus erythematosus.

    Lupus·2011
    Same author

    Drug-induced subacute cutaneous lupus erythematosus.

    Lupus·2010
    Same author

    Dermatology position paper on the revision of the 1982 ACR criteria for systemic lupus erythematosus.

    Lupus·2004
    Same author

    Vancomycin-induced linear IgA bullous disease presenting as toxic epidermal necrolysis.

    Clinical and experimental dermatology·2004
    Same author

    Update on the management of cutaneous lupus erythematosus.

    The British journal of dermatology·2004
    Same journal

    Hypoactive Sexual Desire Disorder in Menopausal Women: Dermatologic Implications of Antiandrogen and Testosterone Therapy.

    Journal of the American Academy of Dermatology·2026
    Same journal

    Incise parallel, section perpendicular to the dermatoglyphs for diagnosis of acral melanocytic lesions-A comment on Thakker et al.

    Journal of the American Academy of Dermatology·2026
    Same journal

    Response to Xue et al, "Defining super-responders is not the same as predicting rituximab response in pemphigus".

    Journal of the American Academy of Dermatology·2026
    Same journal

    Comment on Nie et al. (2026) 'Suicidality Reports in Acne Patients Treated with Isotretinoin and Concomitant Antidepressants: A Descriptive Analysis of FDA Adverse Event Reporting System Data'.

    Journal of the American Academy of Dermatology·2026
    Same journal

    Defining super-responders is not the same as predicting rituximab response in pemphigus.

    Journal of the American Academy of Dermatology·2026
    Same journal

    Eosinophilic fasciitis induced by checkpoint inhibitors: a retrospective multicenter case-series, comparison with eosinophilic fasciitis unrelated to checkpoint inhibition and literature review.

    Journal of the American Academy of Dermatology·2026
    See all related articles

    Area of Science:

    • Dermatology
    • Immunodermatology

    Background:

    • Bullous pemphigoid (BP) is an autoimmune blistering disease.
    • The vesicular variant of BP presents with small, tense vesicles, differing from typical large bullae.

    Observation:

    • A patient presented with a pruritic eruption resembling dermatitis herpetiformis (DH).
    • The patient subsequently developed large bullae characteristic of BP.
    • Histologic and immunofluorescence findings confirmed BP.

    Findings:

    • The patient's presentation mimicked DH but was diagnosed as a vesicular BP variant.
    • Systemic corticosteroids were initially effective.
    • Methotrexate was required for sustained lesion clearance during corticosteroid tapering, a novel observation for this BP variant.

    Related Experiment Videos

    Implications:

    • This case expands the clinical spectrum of vesicular bullous pemphigoid.
    • It suggests that combination therapy may be necessary for managing refractory cases.
    • Further research into the treatment of BP variants is warranted.