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[Transfusional malaria in France (1960-1979) (author's transl)]
Abstract:
Transfusional Malaria is not a rare condition in France: in the past 20 years, 110 cases were cited in the literature and/or reported to us in answers to a recent questionnaire. Of these, 24 cases occurred between 1960 and 1969 and 78 between 1970 and 1979. This apparent increase in occurrence in the past decade is most probably due to the increase in the number of transfusions of whole blood or fresh fractions containing infected erythrocytes, although population exchanges with inter-tropical Africa may also play a preponderant role. Our study confirms that Plasmodium falciparum is the most prevalent pathogen responsible for this condition in France; it caused 84% of cases in the past five years. We think this point must be taken in account by the legislator.
Insights
Transfusional malaria cases in France are increasing, with Plasmodium falciparum being the most common cause. This highlights the need for legislative attention to blood transfusion safety and malaria prevention.
Area of Science:
- Medical Science
- Infectious Diseases
- Public Health
Background:
- Transfusional malaria, while not common, presents a significant risk in France.
- Historically, cases have been documented, with a notable increase observed in recent decades.
Purpose of the Study:
- To analyze the incidence and trends of transfusion-transmitted malaria in France.
- To identify the primary causative pathogen of transfusional malaria in the French context.
- To provide evidence for potential legislative and public health interventions.
Main Methods:
- Literature review and analysis of reported cases of transfusional malaria in France over a 20-year period.
- Statistical analysis of case distribution across different decades.
- Identification of Plasmodium species responsible for infections.
Main Results:
- 110 cases of transfusional malaria were reported in France over the past 20 years, with a marked increase from 24 cases (1960s) to 78 cases (1970s).
- Plasmodium falciparum was identified as the predominant pathogen, accounting for 84% of cases in the last five years.
- Increased blood transfusions and population movements from inter-tropical Africa are potential contributing factors.
Conclusions:
- Transfusional malaria represents a growing concern in France, necessitating enhanced vigilance.
- Plasmodium falciparum is the primary malaria parasite transmitted through blood transfusions in France.
- Legislative measures and improved screening protocols are recommended to mitigate transfusion-transmitted malaria risks.