[HL-A antigenicity in bladder tumors]

30 patients with papillary transitional bladder tumours were treated by TUR. The stage O and A tumour specimens obtained were examined for presence or loss of antigenicity by the specific red cell adherence test (SRCA). The patients were followed up between 4 and 17 years. A correlation between loss of antigenicity and secondary occurrence of tumours with more aggressive biological behaviour was apparent. Possible therapeutic consequences are discussed.