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Related Experiment Videos

Candida pericarditis

R H Eng, P Sen, K Browne

    The American Journal of Medicine
    |April 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Purulent pericarditis caused by Candida species is rare. This case details Candida tropicalis pericarditis developing after urinary bladder colonization, treated successfully with Amphotericin B, though the patient later died from unrelated causes.

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    Area of Science:

    • Infectious Diseases
    • Cardiology
    • Mycology

    Background:

    • Purulent pericarditis is an uncommon condition.
    • Infections of the pericardium by Candida species are exceptionally rare, with limited documented cases in medical literature.

    Observation:

    • A male patient presented with Candida tropicalis colonization of the urinary bladder.
    • Subsequently, the patient developed Candida tropicalis pericarditis.

    Findings:

    • Intravenous Amphotericin B was administered for treatment.
    • Therapeutic drug monitoring revealed pericardial fluid Amphotericin B levels at approximately 50% of serum concentrations.
    • Microbiologic cure of the pericarditis was achieved with Amphotericin B therapy.

    Implications:

    Related Experiment Videos

    • This case highlights a rare presentation of invasive fungal infection.
    • It underscores the potential for Candida species to cause serious infections beyond typical sites.
    • The findings support the use of Amphotericin B in managing Candida pericarditis, even with reduced pericardial fluid drug levels.