Canine distemper virus titration in ferret peritoneal macrophages

The sensitivity of a ferret peritoneal macrophage fluorescent antibody technique for assay of various strains of canine distemper virus was investigated. The macrophage system was compared with established methods of titration in canine kidney cell culture, Vero cell culture, and embryonated chicken eggs. It was found to be as sensitive as and in several instances more sensitive than the established methods.