Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Arthrography using perfluorocarbon compounds

D R Enzmann, S Young

    Investigative Radiology
    |January 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Perfluorocarbon compounds show excellent knee joint visualization for arthrography up to 24 hours. However, leakage and inflammatory reactions occurred post-24 hours in animal models.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Sodium MR Neuroimaging.

    AJNR. American journal of neuroradiology·2021
    Same author

    Providing professional mammography services: financial analysis.

    Radiology·2001
    Same author

    An unusual case of retinitis.

    Lancet (London, England)·2000
    Same author

    A self-learning predictive model of articulator movements during speech production.

    The Journal of the Acoustical Society of America·2000
    Same author

    The association between early life lung function and wheezing during the first 2 yrs of life.

    The European respiratory journal·2000
    Same author

    Sonography, CT, and MR imaging: a prospective comparison of neonates with suspected intracranial ischemia and hemorrhage.

    AJNR. American journal of neuroradiology·2000
    Same journal

    Iodinated Contrast Media Hypersensitivity in 115,966 Patients: Risk Factors, Severity Profiles, and the Impact of Iodine Concentration on Reaction Risk.

    Investigative radiology·2026
    Same journal

    Improvement of Lung Nodule Volumetric Accuracy with Photon-counting Computed Tomography Over Energy-integrating Computed Tomography in Low-dose Screening: A Phantom Study.

    Investigative radiology·2026
    Same journal

    Photon-counting CT in Anterior Cervical Discectomy and Fusion: Improved Metal Artifact Reduction and Impact on Bone Fusion Assessment.

    Investigative radiology·2026
    Same journal

    Quantitative Synthetic MRI in Body Imaging: Technical Basis, Current Applications, and Future Directions.

    Investigative radiology·2026
    Same journal

    Nonclinical Safety Assessment of Digadoglucitol, a Novel Magnetic Resonance Imaging Contrast Agent for the Central Nervous System.

    Investigative radiology·2026
    Same journal

    Artificial Intelligence-Enhanced Identification of Incidental Findings in Prostate MRI.

    Investigative radiology·2026
    See all related articles

    Area of Science:

    • Biomedical Imaging
    • Radiology
    • Orthopedics

    Background:

    • Arthrography requires effective contrast agents for joint imaging.
    • Perfluorocarbon compounds are being explored for various medical applications.

    Purpose of the Study:

    • To evaluate the efficacy and safety of perfluorocarbon compounds as contrast agents for knee arthrography.
    • To assess the duration of contrast retention and potential tissue reactions.

    Main Methods:

    • Injection of neat liquid and emulsion of perfluorocarbon compounds into canine knee joints and a human cadaver.
    • Evaluation of joint structure delineation over time.
    • Histopathological analysis of joint tissues using light microscopy.

    Main Results:

    Related Experiment Videos

    • Excellent delineation of joint structures was achieved for up to 24 hours.
    • Contrast agents leaked from the joint capsule into surrounding tissues after 24 hours.
    • Histopathology revealed synovial proliferation and foreign-body granuloma reactions.
    • No apparent adverse clinical effects were observed in test animals.

    Conclusions:

    • Perfluorocarbon compounds demonstrate potential for short-term knee arthrography.
    • Further research is needed to address the leakage and inflammatory responses for long-term applications.