Related Experiment Video
Updated: Aug 12, 2026

A Reference Broth Microdilution Method for Dalbavancin In Vitro Susceptibility Testing of Bacteria that Grow Aerobically
Published on: September 9, 2015
Abstract:
There has been minimal utilization of pharmacologic principles in the establishment of treatment programs for many infectious diseases. Drugs with markedly different half-lives and peak levels in serum have been prescribed at the same dosage intervals. No attempt has been made to determine if the efficacy of dosing programs in which levels in serum that exceed bactericidal levels are achieved but in which doses are administered infrequently is greater than or equal to that of current programs. Double-blind studies of therapeutic programs in which drugs with different pharmacokinetic properties are compared are the only means of eliminating the current confusion regarding dosing practices.
More Related Videos
Related Concept Videos
Rational Dosage Regimen: Maintenance Dose and Loading Dose
In most cases, drugs are administered repetitively or infused continuously to maintain a steady-state concentration in the body. At a steady state,...
Dosage Regimens: Designs and Approaches
Dosage Interval and Administration Route: Determination Methods
Determination of Multiple Dosing Parameters: Steady-State, Minimum and Maximum Concentrations
Drug Dosing: Infants and Children
Pharmacokinetics in Pediatric Patients: Drug Excretion

