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[Observations on polymyalgia rheumatica]

K Krug, P Hanke, E G Preuss

    Zeitschrift Fur Die Gesamte Innere Medizin Und Ihre Grenzgebiete
    |December 15, 1980
    PubMed
    Summary
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    Polymyalgia rheumatica can co-occur with giant cell arteritis, causing severe pain and headache. Humoral reactions associated with this condition rapidly improve with glucocorticoid treatment.

    Area of Science:

    • Rheumatology
    • Immunology
    • Vascular Medicine

    Context:

    • Polymyalgia rheumatica (PMR) can present with symptoms overlapping giant cell arteritis (GCA).
    • This overlap includes involvement of the shoulder girdle, pelvic girdle, and temporal arteries.
    • Severe pain, particularly headache, can be a dominant feature.

    Purpose:

    • To describe the clinical presentation and treatment response of patients with polymyalgia rheumatica co-occurring with giant cell arteritis.
    • To investigate the humoral and immunological aspects of this combined condition.

    Summary:

    • Observations of 14 patients with this overlapping condition confirmed severe, generalized humoral reactions.
    • These reactions were rapidly reversible upon treatment with glucocorticoids.

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  • Immunological findings were not specific and require further investigation.
  • Impact:

    • Highlights the importance of recognizing the potential co-occurrence of PMR and GCA.
    • Demonstrates the efficacy of glucocorticoids in managing associated humoral abnormalities.
    • Underscores the need for further research into the specific immunological markers of this condition.