[Effect of metoclopramide on complaints of reflux disease]

By sequence analysis was proved that metoclopramide (cerucal, 3 x 10 mg p.o.) in comparison to placebo removes or relieves typical complaints of the reflux disease. Still one week after the end off the treatment with metoclopramide the gastrooesophageal reflux under fasting conditions was significantly decreased compared with the beginning of the treatment, whereas the reflux stimulated under pentagastrin did not show a remaining influence.