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Therapeutic drug analysis and the clinical laboratory
The American Journal of Medical Technology
|March 1, 1981
Abstract:
This paper presents a general review of the rapidly expanding area of therapeutic drug monitoring and discusses the reasons for measuring serum drug levels. The assay methods commonly used in the clinical laboratory--including gas chromatography, high pressure liquid chromatography, radioimmunoassay, enzyme multiplied immunoassay and fluorescent immunoassay--are discussed. Unique characteristics of the commonly monitored drugs are presented.