Related Experiment Videos
[The dopaminergic system and aldosterone secretion. II. Effect of L-dopa and dexamethasone on aldosterone
Bollettino Della Societa Italiana Di Biologia Sperimentale
|November 30, 1980
Abstract:
The authors studied the blood aldosterone, cortisol, and kalium levels, the plasma renin activity and the aldosterone urinary excretion following L-Dopa (0,50 g per os) administration in five patients affected by hypertension and six healthy control subjects, before and after the CRF-ACTH system suppression. The observed pattern shows that the aldosterone biosynthesis is inhibited also after the CRF-ACTH system has been suppressed. Therefore the authors conclude that the inhibiting action of L-Dopa on the aldosterone biosynthesis is mediated by the dopaminergic system stimulation.