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[Pityriasis lichenoides (author's transl)]

M P Franc, D Barrut, G Moulin

    Annales De Dermatologie Et De Venereologie
    |January 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

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    Pityriasis lichenoides presents in three main clinical patterns and can last from weeks to years. This inflammatory condition, originating from angiitis, shows no specific immunologic disorder and may improve with dapsone or photochemotherapy.

    Area of Science:

    • Dermatology
    • Pathology

    Context:

    • Pityriasis lichenoides is a rare skin condition with variable clinical presentations and duration.
    • Understanding its pathogenesis and treatment options is crucial for effective patient management.

    Purpose:

    • To review the literature on pityriasis lichenoides.
    • To analyze clinical patterns, disease course, and histopathological findings in 34 personal cases.
    • To investigate immunologic aspects and evaluate treatment outcomes.

    Summary:

    • Pityriasis lichenoides exhibits three primary clinical patterns: maculo-papular, leukomelanodermal, and necrotic.
    • The disease course is highly variable, ranging from weeks to months or even years.
    • Histopathology reveals angiitis with lymphocytic infiltration, secondary epidermal invasion, and focal parakeratosis.

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  • No specific immunologic disorder is identified; immunohistopathology is typically normal, with rare IgM or C3 deposits and no circulating immune complexes.

    • Impact:

    • This review provides a comprehensive overview of pityriasis lichenoides, aiding in diagnosis and classification.
    • Findings suggest that dapsone and photochemotherapy may be beneficial treatment options.
    • Further research into the underlying mechanisms of pityriasis lichenoides could lead to novel therapeutic strategies.