Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Intraocular irrigating solutions for pars plana vitrectomy. A prospective, randomized, double-blind study

W E Benson, J G Diamond, W Tasman

    Archives of Ophthalmology (Chicago, Ill. : 1960)
    |June 1, 1981
    PubMed
    Summary

    Glutathione-bicarbonate-Ringer's solution (BSS Plus) reduced early corneal swelling after vitrectomy compared to lactated Ringer's solution. No long-term differences or complications were observed between the solutions.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Patient-initiated second medical opinions: their necessity and economic cost.

    Retina (Philadelphia, Pa.)·2002
    Same author

    Ten-year follow-up from the CRYO-ROP study.

    Archives of ophthalmology (Chicago, Ill. : 1960)·2001
    Same author

    Surgical management of macular holes: a report by the American Academy of Ophthalmology.

    Ophthalmology·2001
    Same author

    Safety of indocyanine green angiography during pregnancy: a survey of the retina, macula, and vitreous societies.

    Archives of ophthalmology (Chicago, Ill. : 1960)·2001
    Same author

    Diabetes and retinopathy.

    Ophthalmology·2000
    Same author

    General Mikhail Kutuzov: one-eyed defender of Moscow.

    Documenta ophthalmologica. Advances in ophthalmology·2000

    Area of Science:

    • Ophthalmology
    • Corneal Physiology
    • Surgical Solutions

    Background:

    • Corneal swelling is a potential complication following intraocular surgery.
    • Choosing the appropriate irrigation solution is crucial for minimizing ocular tissue trauma.
    • Pars plana vitrectomy requires sustained intraocular irrigation, necessitating safe and effective solutions.

    Purpose of the Study:

    • To compare the effects of glutathione-bicarbonate-Ringer's solution (BSS Plus) versus lactated Ringer's solution on corneal swelling post-vitrectomy.
    • To evaluate the safety and efficacy of BSS Plus in minimizing early postoperative corneal edema.

    Main Methods:

    • Prospective, randomized, double-blind study design.
    • Comparison of BSS Plus and lactated Ringer's solution for intraocular irrigation during pars plana vitrectomy.

    Related Experiment Videos

  • Assessment of corneal thickness at the first and seventh postoperative days.

    • Main Results:

    • BSS Plus demonstrated significantly less corneal swelling on postoperative day one compared to lactated Ringer's solution.
    • No significant difference in corneal thickness was observed between the two solutions by postoperative day seven.
    • No correlation found between corneal thickness increase and irrigation duration, volume, or lens status.
    • No persistent corneal complications were reported for either solution.

    Conclusions:

    • BSS Plus offers an advantage in reducing early postoperative corneal swelling after pars plana vitrectomy.
    • Both BSS Plus and lactated Ringer's solution appear safe for intraocular irrigation, with no long-term adverse effects on the cornea.
    • The choice of irrigation solution may impact immediate postoperative corneal hydration, but not long-term outcomes.