Related Experiment Video
Updated: Aug 18, 2026
06:55
Diagnosis of Neoplasia in Barrett’s Esophagus using Vital-dye Enhanced Fluorescence Imaging
Published on: May 11, 2014
DNA distribution patterns of preneoplastic cells and their interpretation. Stomach and cervix uteri
Oncology
|January 1, 1981
Abstract:
Gastric mucosa and smears of the cervix uteri - both under normal conditions and in different pathological stages - were processed by flow cytometry. DNA distribution patterns were measured and compared. Special interest was focused on chronic atrophic gastritis (CAG), checking its biological value and clinical importance with precancerous stages of the cervix uteri. In rare, distinct cases, CAG revealed carcinoma indicating DNA distribution patterns as distinct cases of dysplasia and Ca in situ of the cervix.
Related Concept Videos
02:07Tumor Progression
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
01:24Cellular Adaptation IV: Dysplasia and Metaplasia
DysplasiaDysplasia refers to abnormal changes in the size, shape, and organization of mature cells, characterized by pleomorphism, nuclear abnormalities, and increased mitotic activity. It commonly affects epithelial tissues, including the cervix, gastrointestinal tract, respiratory mucosa, and endometrium. Although it may occur alongside hyperplasia, dysplasia is not a true adaptive response but a preneoplastic change with potential to progress to cancer.When confined above the basement...