Related Experiment Videos
The mast cell and eosinophil in nasal secretion
Annals of Allergy
|August 1, 1977
Summary
An improved Hansel staining method effectively identifies mast cells in nasal smears. This diagnostic advancement revealed mast cells in 87% of children and 95% of adults at an allergy clinic.
Area of Science:
- Allergy and immunology
- Cytology
- Diagnostic pathology
Background:
- Nasal smears are used for diagnosing respiratory conditions.
- Identifying specific cells like mast cells can aid in allergy diagnosis.
- Previous staining methods may have limitations in sensitivity.
Purpose of the Study:
- To evaluate an improved Hansel staining technique for identifying cells in nasal smears.
- To determine the prevalence of mast cells in nasal smears of patients visiting an allergy clinic.
Main Methods:
- An improved Hansel staining protocol was utilized.
- Nasal smears were collected from patients attending an allergy clinic.
- The presence of mast cells, eosinophils, and other cells was assessed.
Main Results:
- The enhanced staining method allowed for clear identification of various cells, including mast cells.
- Mast cells were detected in 87% of pediatric patients.
- Mast cells were identified in 95% of adult patients.
Conclusions:
- The improved Hansel staining is a valuable tool for identifying mast cells in nasal smears.
- A high prevalence of mast cells was observed in patients with allergic conditions.
- This method can aid in the diagnosis and management of allergic diseases.