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Proticine typing of serologically defined Proteus strains
Acta Microbiologica Academiae Scientiarum Hungaricae
|January 1, 1981
Summary
Proticine (bacteriocin) typing effectively differentiates Proteus vulgaris and Proteus mirabilis strains for epidemiological studies. This method, combined with antigen analysis, aids in tracking these bacterial infections.
Area of Science:
- Microbiology
- Bacteriology
- Epidemiology
Background:
- Proteus species are significant in clinical and environmental settings.
- Accurate strain differentiation is crucial for epidemiological investigations.
- Existing typing methods may have limitations in differentiating Proteus species.
Purpose of the Study:
- To evaluate the efficacy of proticine (bacteriocin) typing for classifying Proteus strains.
- To assess the correlation between proticine types and serological classifications.
- To determine the utility of proticine typing in epidemiological tracing of Proteus vulgaris and Proteus mirabilis.
Main Methods:
- Serological definition of Proteus strains (P. vulgaris, P. mirabilis, P. morganii, P. rettgeri, P. inconstans).
- Classification using proticine typing (P type for production, S type for sensitivity) with Cradock-Watson's method.
- Testing typability percentages for P. vulgaris and P. mirabilis using P and S methods.
Main Results:
- P. vulgaris showed low typability by P method (4.1%) but higher by S method (41.6%).
- P. mirabilis exhibited higher typability: 60.1% by P method and 48.9% by S method.
- A significant correlation was found between P/S types and serogroups/serotypes in P. mirabilis; other species were largely untypable.
Conclusions:
- Proticine typing, particularly the P/S method, demonstrates high differentiating value for P. vulgaris and P. mirabilis.
- Combined with O and H antigen determination, proticine typing enhances epidemiological tracing capabilities.
- The method shows limited utility for P. morganii, P. rettgeri, and P. inconstans.