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Thermodilution cardiac output--a systematic error

W B Runciman, A H Ilsley, J G Roberts

    Anaesthesia and Intensive Care
    |May 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

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    This study confirmed a systematic error in thermodilution cardiac output measurement, likely due to thermal indicator loss. A correction factor is proposed to improve accuracy in cardiac output assessments.

    Area of Science:

    • Cardiovascular Physiology
    • Medical Instrumentation

    Background:

    • Thermodilution is a common method for measuring cardiac output.
    • Accurate cardiac output measurement is critical for patient management.

    Purpose of the Study:

    • To investigate the systematic error in thermodilution cardiac output (CO) measurement.
    • To determine the mechanism and magnitude of this error.
    • To propose a method for improving thermodilution accuracy.

    Main Methods:

    • Compared 171 thermodilution CO measurements with simultaneous dye dilution measurements in dogs.
    • Utilized Swan-Ganz catheters for thermodilution measurements.
    • Evaluated measurements across a wide range of cardiac outputs and varying conditions.

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    Main Results:

    • Confirmed a consistent, systematic error in thermodilution CO measurements.
    • The observed error magnitude was comparable to previously reported findings.
    • Identified potential indicator loss between injection and detection as the primary mechanism.

    Conclusions:

    • The thermodilution technique exhibits a systematic underestimation of cardiac output.
    • Thermal indicator loss is the proposed cause of this measurement error.
    • Implementing a correction factor for indicator loss may enhance thermodilution accuracy.