[Effect of 60Co gamma rays and fast neutrons on intravascular platelet aggregation and vessel wall prostacyclin
Abstract:
The influence of gamma-rays 60Co and fast neutrons on intravascular platelet aggregation and prostacyclin activity of the vascular wall has been studied. It has been shown that 1-6 hours after irradiation of CBA mice, a great number of bone marrow platelets clump to form fibrin fibrils that often close completely the vascular lumen. Experiments with irradiated rats and guinea-pigs have demonstrated the reduction of prostacyclin-like activity in the abdominal aorta wall.
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