Clinical evaluation of bromperidol versus haloperidol in psychotic patients

The purpose of this study was to compare the activity of bromperidol to that of haloperidol, as an initial treatment on admission of psychotic patients. In general, patients reacted equally on both drugs, showing a marked improvement in most of the scored psychiatric elements. After 2 weeks, an improvement in the energy score was noticed for bromperidol, but not for haloperidol, which emphasizes the disinhibiting effect of bromperidol. Most frequent side-effects were tremor, parkinsonism and acathisia.